Unfortunately, melasma is a chronic condition. Relapses are possible, especially if you are exposed to the sun frequently and/or on hormones. Abruptly stopping application of The Spot Cream can also cause this, instead we recommend slowly weaning off by using a maintenance cream, such as The Spot Cream Nurture. Overuse of The Spot Cream can also cause deeper pigmentation called “post inflammatory hyperpigmentation”, we recommend following the directions regarding application provided by your Musely doctor. Where can I find instructions on how to use my treatment?