Some people can have reactions to these medications. If you are concerned about possible reactions, you can do a small “Test Spot” by putting a small amount of cream in an inconspicuous area like the inner arm for a few days. If you don’t notice any reaction, it is safe to start using the cream on the treatment area.
Common side effects include minor and temporary skin irritations including mild itching, peeling, darkening, stinging and reddening of the skin (irritant contact dermatitis) especially around the mouth and eye areas with these products. Adding a moisturizer or Aquaphor/Vaseline may help.
You can also consider taking a break from using the medication until your side effects subside (approximately 3-7 days. When you restart treatment, use the medication with a thick moisturizer, such as Aquaphor/Vaseline.
If the side effects do not improve over time, stop using the cream and apply OTC (over-the-counter) 1% hydrocortisone (Cortizone 10) and cut out any other potentially irritating ingredients (alpha- or beta-hydroxy acids, salicylic acid, glycolic toners, retinols, scrubs, etc). Please seek medical advice immediately if you experience any of the following: severe burning, itching, crusting, or swelling of treated areas (possible allergic contact dermatitis) and any unusual skin discoloration.