We recommend incorporating The Red Set and The Anti-Aging Night Cream very slowly. Start by using The Red Set once a day before going to twice a day. This allows the skin to adjust to the ingredients. After you have adjusted to The Rosacea Cream, then add The Anti-Aging Night Cream back into your routine, slowly, 1-2x a week and only to areas of your face where you did not apply The Rosacea Cream. Once adjusted, apply The Rosacea Cream first, wait 5 to 10 minutes, followed by The Anti-Aging Night Cream. Use a moisturizer after The Anti-Aging Night Cream.