You should stop use of any other FaceRx prescription medications at least a week prior to using The Spot Peel. You can still use a cleanser, a moisturizer, and SPF during this time before using The Spot Peel. You should conduct a small patch test to see how your skin reacts to the treatment on your jaw or forehead at least one day before application. Please also ensure that the skin on your face is not broken or damaged, as the treatment should not be applied to damaged areas.