Why can’t I use The Neck Cream during the day? June 12, 2020 05:58 Updated The Neck Cream contains tretinoin which should only be used at night. Related articles Do the dark spots come back if you stop using The Spot Cream? How do I apply The Neck Cream? What are the possible side effects of The Neck Cream? How long does it take to see results with The Neck Cream? How long does it take to see results with The Night Cream?