How long does it take to see results with The Night Cream? June 12, 2020 05:48 Updated Patients will typically see results in 6-8 weeks. Related articles Can I use The Night Cream during the day? Does The Night Cream treat...? Do the dark spots come back if you stop using The Spot Cream? Can I order The Night Cream alone? Can I cancel Auto-Refill or change my refill date?